WBC-White blood cells MCQs regarding wbc and more Health exams preparation
Dr Chaitanya Joshi
Revision
RBC revision class
WBC stands for White Blood Cells, which are a component of the immune system responsible for defending the body against infections and diseases.
Normal character of WBC
Anemia classification
Anemia causes
Treatment of anemia?
Introduction
WBC= white blood cells
 |
| WBC Types normal |
AKA-> leukocytes
Leuko=white
Normal count? 4-11
Increased count=leukocytosis
Decreased count= leukopenia
Types Normal character of WBC
- Granulocytes
- Neutrophils
- Basophils
- Eosinophils
- Agranulocytes
- Lymphocytes
- Monocytes
Neutrophils
40-70% of total WBC in blood
Also called polymorphonuclear cells
Have multilobed nucleus
Job description: Phagocytosis and killing of pathogen
Have enzyme for digestion in their granules
Neutrophilia- in infection
Leukemia in cancer (hematological malignancy)
Eosinohils
1-4% of total WBC
Destroy parasites (helminths)
Increases in
allergic conditions
Parasitic infestation
Aasthma
Allergic rhinitis
Urticaria etc
Degrade histamine
They stain by eosin pigment in H&E stain so called eosinophil
Basophil
Less than 1%
Role in anti-inflammatory process
Resemble in structure of mast cell of the connective tissues
Have IgE receptor in their cell surface
Secrete histamine leading to IgE mediated immune reaction(type I hypersensitivity)
Lymphocytes
20-40% of total WBC
Types
B lymphocytes (maturation in
bone marrow then goes to secondary lymphoid tissues)
T lymphocytes (maturation/activation in thymus)
B-lymphocytes
Humoral immune response
They differentiate into plasma cells and memory cells
Secrete/synthesize antibodies
Remember antigen for long run
Immunization?
T-lymphocytes
Cell mediated immune response
Have t-cell receptors
Different types according to receptors
CD4-helper, CD8-cytotoxic, memory t-celletc
They recognize and destroy antigen/viruses
Monocytes
2-8 % of total WBCs
If they go to the tissue they change into the macrophages
Macrophges are antigen presenting cells-process the antigen
Osteoclasts, Kupffer cells, mesangial cells, microglial cells, sinusoidal cells, histocytes all are monocytes
NK cells
Role in virus infected cell elimination
Cancecr cell killing
Help neutrophils and macrophages
Thank you
Multiple Choice Questions in WBC
1. The average life span of WBC is:
2 to 4 hours
2 to 4 days
120 days
365 days
Ans: b (2 to 4 days)
2. Leukemia normally means:
Excessive production of RBC
Excessive production of Platelets
Excessive production of WBC
Reduction in number of WBC
Ans: c (Excessive production of WBC)
3. The process of development and maturation of WBC is known as:
Erythropoiesis
Hematopoiesis
Leucopoiesis
Neuropoiesis
Ans: c ( Leucopoiesis)
4. In adults, WBCs count should be…………………… of blood.
1000-2500/mm3
2500-3000/mm3
3000-3500/mm3
4000-11000/mm3
Ans: d (4000- 11000/mm3)
5. White Blood Cells are also known as ……………….. blood cells.
Colorless
Red
Black
Green
Ans: a (Colorless)
6. The basophils of white blood cells liberates…………….
Heparin
Serotonin
Histamine
All of these
Ans: d (all of these)
7. Which of the following is correct subtype of lymphocytes?
G cell
P cell
T cell
U cell
Ans: c (T cell)
8. Lymphocytes and phagocytes are the types of
Erythrocytes
Leukocytes
Platelets
Antibodies
Ans: b ( Leukocytes)
9. What do WBCs do?
Carry oxygen from the lungs.
Carry waste products from the cells.
Fight against infection.
Help stop bleeding by forming clots.
Ans: c ( fight against infection)
10. What are neutrophils?
Immature Red Blood Cell
A type of White Blood Cell
A type of Platelet
A type of Bacteria
Ans: b (A type of White Blood Cell)
11. What is severe neutropenia?
An absolute neutrophil count (ANC) of less than 500
An ANC of less than 1000
An ANC of less than 50
An ANC of less than 25
Ans: a (An ANC of less than 500)
What is your say on this?