Hypothyroidism and lipid profiyare closely related. Here’s ansito your question:
Yes, hypothyroidism can increase LDL (low-density lipoprotein) cholesterol levels.
Here’s why:
Thyroid hormones (mainly T3) help regulate lipid metabolism.
In hypothyroidism, low thyroid hormone levels lead to reduced LDL receptor activity in the liver.
This decreases the clearance of LDL from the bloodstream, causing elevated LDL levels.
It may also lead to increased total cholesterol and triglycerides, particularly in overt hypothyroidism.
Even subclinical hypothyroidism (normal T3/T4 but elevated TSH) can mildly increase LDL cholesterol.
Clinical relevance:
In patients with high LDL or dyslipidemia, checking thyroid function is recommended, as treating hypothyroidism often improves lipid profiles.
