Here are some important signs and names in medical science grouped by domain.
Medical Imaging / Pathology Descriptions
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Bird beak appearance – tapering of the distal esophagus (achalasia)
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Ground-glass opacity – hazy lung opacity resembling frosted glass
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Onion-skin appearance – concentric layering seen in some bone lesions or vessel walls
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Honeycomb lung – clustered cystic air spaces in lung fibrosis
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Double bubble sign – two adjacent fluid-filled structures on abdominal imaging (duodenal atresia)
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Sunburst appearance – radiating spicules from a central lesion (osteosarcoma)
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Apple core lesion – constricted, irregular narrowing of the colon (colon cancer)
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Popcorn calcification – coarse, lobulated calcifications (pulmonary hamartoma)
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Eggshell calcification – thin rim of calcification around lymph nodes
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String sign – thin stream of contrast through a narrowed bowel segment (Crohn’s disease)
Microscopy / Lab Descriptions
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Spaghetti and meatballs appearance – Malassezia yeast and hyphae mix on KOH prep
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Starry-sky appearance – lymph node histology in Burkitt lymphoma
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Owl’s eye appearance – CMV-infected cells
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Coffee bean nuclei – groove-like nuclear indentations in ovarian granulosa cells
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Crushed glass appearance – cytoplasm in certain hepatitis cases
Dermatology / Physical Exam
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Butterfly rash – malar rash in lupus erythematosus
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Cobblestone mucosa – mucosal swelling pattern (Crohn’s disease)
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Strawberry tongue – erythematous tongue with enlarged papillae (scarlet fever, Kawasaki disease)
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Target lesion – concentric rings as in erythema multiforme
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Auspitz sign – pinpoint bleeding spots when psoriasis scales are removed
