Mycoplasma pneumonia : The dangerous walking talking pneumonia
Introduction
Mycoplasma pneumonia is a common cause of respiratory tract infections in
adolescents. It can present with fever, cough, and infiltrates on chest X-ray.
In some cases, mycoplasma infection can also cause skin manifestations such as
vesicles or blisters.
Presenting symtoms of mycoplasma pneumonia
The patient is presenting with symptoms suggestive of Mycoplasma pneumonia,
including fever, cough, and infiltrates on chest X-ray. The presence of
vesicles or blisters on the skin further supports the possibility of
Mycoplasma-induced skin manifestations.
57.Following drugs are effective against Mycoplasma pneumoniae except:
a. Clarithromycin
c. Amoxycillin
b. Rifampicin
d. Doxycycline
T
Ans: ‘c’
Solution
Mycoplasma pneumoniae lacks cell wall. Bacterial membrane contains sterol for stability.
Antimicrobial activity of Amoxycillin is via inhibition of cell wall synthesis which has no role in Mycoplasma.
Penicillin ineffective since mycoplasma have no cell wall.
Treatment (Mycoplasma)
Macrolides
Doxycycline or
Fluoroquinolone
3
MOA
Macrolides
Clarithromycin
Azithromycion
inhibit protein synthesis by blocking translocation: blinds to 23srRNA of 50s ribosomal subunit
Bacteriostatic
Tetracyclines
Tetracycline
Doxycycline
Bind to 30S & prevent attachment of aminoacyl-t RNA Bacteriostatic
Rifamycin
Rifampin
Inhibit DNA dependent RNA polymerase
Rifabutin
Fluroquinolones
Ciprofloxacin
Norfloxacin
Levofloxacin
Inhibit prokaryotic
enzymes topo isomerase II (DNA gyrase) & topoisomerase IV.
FAQs:
1. Can Mycoplasma pneumonia cause skin manifestations?
Yes, in some cases, Mycoplasma pneumonia can cause skin manifestations such as
vesicles or blisters.
2. How is Mycoplasma pneumonia diagnosed?
Mycoplasma pneumonia can be diagnosed through serological testing for
Mycoplasma antibodies or PCR testing for Mycoplasma DNA in respiratory
samples.
3. What is the treatment for Mycoplasma pneumonia?
The treatment for Mycoplasma pneumonia involves the use of antibiotics such as
macrolides or tetracyclines.
4. Is Mycoplasma pneumonia contagious?
Yes, Mycoplasma pneumonia is contagious and can spread through respiratory
droplets.
5. Can Mycoplasma pneumonia cause complications?
Yes, Mycoplasma pneumonia can lead to complications such as pneumonia,
bronchitis, or ear infections.
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