WBC-White blood cells MCQs regarding wbc NNC License Preparation Lecture Recorded Videos
RBC revision class
WBC stands for White Blood Cells, which are a component of the immune system responsible for defending the body against infections and diseases.
Normal character of WBC
- Anemia classification
- Anemia causes
- Treatment of anemia?
Introduction
WBC= white blood cells
 |
| WBC Types normal |
- AKA-> leukocytes
- Leuko=white
- Normal count? 4-11
- Increased count=leukocytosis
- Decreased count= leukopenia
Types Normal character of WBC
- Granulocytes
- Neutrophils
- Basophils
- Eosinophils
- Agranulocytes
- Lymphocytes
- Monocytes
Neutrophils
- 40-70% of total WBC in blood
- Also called polymorphonuclear cells
- Have multilobed nucleus
- Job description: Phagocytosis and killing of pathogen
- Have enzyme for digestion in their granules
- Neutrophilia- in infection
- Leukemia in cancer (hematological malignancy)
Eosinohils
- 1-4% of total WBC
- Destroy parasites (helminths)
- Increases in
- allergic conditions
- Parasitic infestation
- Aasthma
- Allergic rhinitis
- Urticaria etc
- Degrade histamine
- They stain by eosin pigment in H&E stain so called eosinophil
Basophil
- Less than 1%
- Role in anti-inflammatory process
- Resemble in structure of mast cell of the connective tissues
- Have IgE receptor in their cell surface
- Secrete histamine leading to IgE mediated immune reaction(type I hypersensitivity)
Lymphocytes
- 20-40% of total WBC
- Types
- B lymphocytes (maturation in
- bone marrow then goes to secondary lymphoid tissues)
T lymphocytes (maturation/activation in thymus)
B-lymphocytes
- Humoral immune response
- They differentiate into plasma cells and memory cells
- Secrete/synthesize antibodies
- Remember antigen for long run
Immunization?
T-lymphocytes
- Cell mediated immune response
- Have t-cell receptors
- Different types according to receptors
- CD4-helper, CD8-cytotoxic, memory t-celletc
- They recognize and destroy antigen/viruses
Monocytes
- 2-8 % of total WBCs
- If they go to the tissue they change into the macrophages
- Macrophges are antigen presenting cells-process the antigen
- Osteoclasts, Kupffer cells, mesangial cells, microglial cells, sinusoidal cells, histocytes all are monocytes
NK cells
- Role in virus infected cell elimination
- Cancecr cell killing
- Help neutrophils and macrophages
Multiple Choice Questions in WBC
1. The average life span of WBC is:
- 2 to 4 hours
- 2 to 4 days
- 120 days
- 365 days
Ans: b (2 to 4 days)
2. Leukemia normally means:
- Excessive production of RBC
- Excessive production of Platelets
- Excessive production of WBC
- Reduction in number of WBC
Ans: c (Excessive production of WBC)
3. The process of development and maturation of WBC is known as:
- Erythropoiesis
- Hematopoiesis
- Leucopoiesis
- Neuropoiesis
Ans: c ( Leucopoiesis)
4. In adults, WBCs count should be…………………… of blood.
- 1000-2500/mm3
- 2500-3000/mm3
- 3000-3500/mm3
- 4000-11000/mm3
Ans: d (4000- 11000/mm3)
5. White Blood Cells are also known as ……………….. blood cells.
- Colorless
- Red
- Black
- Green
Ans: a (Colorless)
6. The basophils of white blood cells liberates…………….
- Heparin
- Serotonin
- Histamine
- All of these
Ans: d (all of these)
7. Which of the following is correct subtype of lymphocytes?
- G cell
- P cell
- T cell
- U cell
- Ans: c (T cell)
8. Lymphocytes and phagocytes are the types of
- Erythrocytes
- Leukocytes
- Platelets
- Antibodies
Ans: b ( Leukocytes)
9. What do WBCs do?
- Carry oxygen from the lungs.
- Carry waste products from the cells.
- Fight against infection.
- Help stop bleeding by forming clots.
Ans: c ( fight against infection)
10. What are neutrophils?
- Immature Red Blood Cell
- A type of White Blood Cell
- A type of Platelet
- A type of Bacteria
- Ans: b (A type of White Blood Cell)
11. What is severe neutropenia?
- An absolute neutrophil count (ANC) of less than 500
- An ANC of less than 1000
- An ANC of less than 50
- An ANC of less than 25
Ans: a (An ANC of less than 500)
