MBBS third year medicine MCQs AIIMS (old Questions)

MBBS third year medicine AIIMS Multiple Choice Questions (MCQs)

Q1. A patient who is being screened for vitamin B-12 deficiency undergoes a Schilling test. In this test, 1 mg of cobalamin is administered intramuscularly 1 hour after the administration of radiolabeled cobalamin. A normal Schilling test (excretion of 10% of the labeled cobalamin in a 24-hour urine specimen) would most likely be seen in which of the following situations?

• (a) Intrinsic factor deficiency
• (b) Chronic pancreatitis
• (c) Surgically absent terminal ileum
• (d) Celiac sprue

Q2. HIV infects cells bearing the CD4 receptor. Which co-receptor is required for HIV to enter the cell?

• (a) CD5
• (b) Chemokine receptor 5 (CCR5)
• (c) Major histocompatibility complex receptor (MHC)
• (d) CD3

Q3. Which of the following is a symptom of acute kidney injury?

• (a) Increased urine output
• (b) Decreased urine output
• (c) Hypertension
• (d) Proteinuria

Q4. Weight loss and malabsorption are commonly seen as features of which of the following conditions?

• (a) Lactose intolerance
• (b) Pernicious anemia
• (c) Lymphocytic colitis
• (d) Small bowel bacterial overgrowth

Q5. Dengue hemorrhagic fever is considered if all the following are present except:

• (a) Systolic blood pressure < 90 mm Hg
• (b) Fever (acute onset of 2–7 days)
• (c) Hemorrhagic manifestations
• (d) Platelet count ≤ 100,000/cu.mm

Q6. An 80-year-old male complains of a 3-day history of a painful rash extending over the left half of his forehead and down to his left eyelid. Physical examination reveals weeping vesicular lesions. What is the most likely diagnosis?

• (a) Impetigo
• (b) Adult chickenpox
• (c) Shingles
• (d) Herpes simplex

Q7. A 25-year-old patient presents with flank pain and fever. What is the most likely diagnosis?

• (a) Acute pyelonephritis
• (b) Renal tuberculosis
• (c) Transitional cell carcinoma
• (d) Pelvic inflammatory disease

Q8. According to Truelove and Witts’ classification, which of the following suggests severe ulcerative colitis?

• (a) >10 bloody stools/day
• (b) Pulse 84/min
• (c) Hemoglobin 10.6 g/dL
• (d) ESR 19 mm in 1 hour

Q9. Regarding pleural effusions, which of the following statements is true?

• (a) A 500 mL pleural effusion is generally easy to detect
• (b) A protein level of <30 g/L suggests an exudate
• (c) In infections, a pleural fluid pH of 7.2 suggests the need for drainage
• (d) Pleural effusions occur more commonly on the left

Q10. Which of the following is not a laboratory indicator of iron deficiency anemia?

• (a) Microcytic red blood cells
• (b) A low serum ferritin
• (c) A low serum TIBC
• (d) A low serum iron

Q11. Which of the following is a cause of bilateral spastic paraparesis?

• (a) Vitamin B12 deficiency
• (b) Cerebellar disease
• (c) Peripheral neuropathy
• (d) Stroke in the internal capsule

Q12. Which one of the following statements about paracetamol poisoning is not true?

• (a) Fifteen tablets may be a fatal overdose
• (b) Oral methionine may be a useful treatment
• (c) Paracetamol levels should be checked 4 hours post-ingestion
• (d) If liver function tests are normal at 4 hours post-ingestion, the liver has not been damaged

Q13. Hyponatremia is defined as a plasma sodium concentration of:

• (a) <115 mmol/L
• (b) <125 mmol/L
• (c) <135 mmol/L
• (d) <145 mmol/L

Q14. Which of the following is a cause of direct hyperbilirubinemia?

• (a) Crigler-Najjar syndrome
• (b) Gilbert syndrome
• (c) G6PD deficiency
• (d) Dubin-Johnson syndrome

Q15. Management of delirium includes:

• (a) Neuroleptics
• (b) Atypical neuroleptics
• (c) Both can be used
• (d) None of the above

Q16. Regarding the SPIKES protocol, which of the following is correct?

• (a) It includes elements of breaking bad news
• (b) It involves mentally preparing to interact with the patient and family
• (c) It emphasizes providing information sensitively
• (d) All of the above

Q17. Evidence-based medicine involves:

• (a) Formulating the management question
• (b) Searching literature and databases for research
• (c) Applying gathered knowledge for the best possible outcome
• (d) All of the above

Q18. Regarding the patient-physician relationship, which statement is true?

• (a) Patients are individuals with problems that present as physical complaints
• (b) Most patients are anxious and fearful
• (c) A professional attitude with warmth and openness helps alleviate patient anxiety
• (d) All of the above

Q19. Which of the following diseases is associated with gross hematuria?

• (a) Subacute bacterial endocarditis
• (b) Cystic kidney disease
• (c) Mesangioproliferative glomerulonephritis
• (d) IgA nephropathy

Q20. Which of the following is an appetite-regulating hormone?

• (a) Amylin
• (b) Ghrelin
• (c) GLP-1
• (d) Secretin