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“description”: “ESR Vs CRP: What are the differences? Subscribe: https://www.youtube.com/@cjoshi0?sub_confirmation=1 Features of ESR (Erythrocyte Sedimentation Rate) Measures the rate at which red blood cells settle in a tube over one hour. Indirect marker of inflammation. Slow response time (takes days to rise and fall). Less sensitive; affected by factors like age, anemia, and pregnancy. Non-specific; can be elevated in infections, chronic diseases, pregnancy, and anemia. Better for tracking chronic inflammatory diseases (e.g., rheumatoid arthritis). Affected by other factors like age, anemia, and plasma protein levels. Normal range varies by age and gender (e.g., ≤20 mm/hr for young adults). Used in conditions like autoimmune diseases, chronic infections, and malignancies. Features of CRP (C-Reactive Protein) Measures the concentration of CRP, a protein produced by the liver in response to inflammation. Direct marker of inflammation. Fast response time (rises within hours, decreases quickly). More sensitive and specific for inflammation. More specific to acute inflammation and infection. Better for detecting and monitoring acute inflammation (e.g., bacterial infections, sepsis). Less affected by external factors. Normal range is typically less than 10 mg/L (may vary slightly by lab). Used in conditions like bacterial infections, sepsis, and cardiovascular risk assessment. NHPC, NPC, NNC, NMC examinations. CTEVT examinations, MBBS and nursing class. —————————————————————– Subscribe: https://www.youtube.com/@cjoshi0?sub_confirmation=1 @cjoshi0 @MysticHealthcare Social Media Platform Link Facebook https://www.facebook.com/chaitanya.com.np Facebook https://www.facebook.com/MysticHealthNP Facebook https://www.facebook.com/theunavailableusername YouTube https://www.youtube.com/@cjoshi0 YouTube https://www.youtube.com/@MysticHealthcare WhatsApp https://wa.me/+9779848843589 WhatsApp https://wa.me/+9779861481571 Instagram https://www.instagram.com/joshi.chaitanya/ Instagram https://www.instagram.com/mystichealthcare/ Instagram https://www.instagram.com/dr_chaitanya_mbbs TikTok https://www.tiktok.com/chaitanya.com.np Reddit https://www.reddit.com/user/cjoshii/ Snapchat https://snapchat.com/add/thecjoshi Pinterest https://www.pinterest.com/cjoshi0/ LinkedIn https://www.linkedin.com/in/cjoshi0/ ———————————————- Subscribe: https://www.youtube.com/@cjoshi0?sub_confirmation=1 LinkedIn https://www.linkedin.com/company/mystic-healthcare-private-limited/ Twitter https://twitter.com/cJoshi0 Twitter https://twitter.com/mystichealthnp Telegram https://t.me/CJoshi0 Viber viber://add?number=9779848843589 Viber viber://add?number=9779861481571 Website https://www.chaitanya.com.np/ Website http://www.mystichealth.com.np/ Website https://www.doctorhealthrx.com/”,
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Most Common Complication of High Myopia

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Myopia, or nearsightedness, and hyperopia, or farsightedness, are both common refractive eye conditions that blur vision. 

Complications of Myopia:

• Myopic crescents (on the temporal side)
• Posterior staphyloma
• Patchy choroidal atrophy within the posterior pole
• Vitreous syneresis
• Breaks in Bruch’s membrane with accompanying choroidal atrophy (lacquer
  cracks)
• Subretinal neovascular membrane with overlying retinal pigment epithelial
  hyperplasia (Foster-Fuchs spot)
• Retinal detachment

Key Concepts on vision:

• Physiological myopia is the
  most common eye disorder worldwide.
• In myopia, parallel rays of
  light focus
  in front of the retina.
• In hypermetropia, parallel
  rays of light focus
  behind the retina.
• A 1 mm change in axial
  length leads to a
  3D change in refraction.
  • Shortening causes
    hypermetropia
  • Lengthening causes
    myopia
• A 1 mm change in corneal
  curvature can lead to
  6D hypermetropia.
• At birth, the eye is normally hypermetropic.
• Optical treatment:
  • Myopia → Concave lens
  • Hypermetropia →
    Convex lens
• Presbyopia: Physiological
  insufficiency of accommodation due to loss of elasticity of the lens capsule
  (age-related).
• Astigmatism: Unequal
  refractive error in two eyes.
• Aniseikonia: Unequal
  image shape/size in the visual cortex.
• Aphakia: Absence of the
  crystalline lens.
  Treatment of choice →
  Posterior chamber IOL implantation.
• The most common eye disorder worldwide is physiological myopia, a refractive error.
• The most common cause of blindness worldwide: Cataract (more than refractive error and aphakia blindness).
• The most common cause of irreversible blindness worldwide: Glaucoma.

Trachoma – Key Points

Introduction

• Definition: A chronic
  infectious eye disease caused by
  Chlamydia trachomatis.
• Transmission: Spread
  through direct contact with infected secretions, contaminated objects, and
  flies.
• Symptoms: Eye redness,
  irritation, discharge, photophobia, and progressive corneal scarring.
• Complications: Corneal
  opacity, trichiasis (inward-growing eyelashes), and blindness.
• Epidemiology: Leading cause
  of infectious blindness globally, prevalent in poor hygiene and low-income
  regions.

Stages of Trachoma (WHO Grading System)

1. TF (Trachomatous Inflammation – Follicular): Presence of five or more follicles (>0.5 mm) in the upper tarsal
   conjunctiva.
2. TI (Trachomatous Inflammation – Intense): Thickened, inflamed upper tarsal conjunctiva with pronounced redness.
3. TS (Trachomatous Scarring):
   Visible scarring of the tarsal conjunctiva.
4. TT (Trachomatous Trichiasis): Inturned eyelashes rubbing against the eyeball.
5. CO (Corneal Opacity):
   Opacity leading to significant visual impairment or blindness.

SAFE Strategy for Trachoma Control
(WHO)

1. S – Surgery: For
   trichiasis to prevent corneal damage.
2. A – Antibiotics: To treat
   active infection and reduce transmission.
3. F – Facial cleanliness:
   Encouraging hygiene to prevent spread.
4. E – Environmental improvement: Ensuring clean water supply and sanitation.

Antibiotics for Trachoma

1. Azithromycin (preferred
   drug)

   • Dose:
     • Adults: 1 g orally, single dose
     • Children: 20 mg/kg (maximum 1 g), single dose
   • Duration: Single-dose treatment, repeated annually in endemic areas.

2. Tetracycline (1%) ophthalmic ointment

   • Dose: Apply to both eyes twice daily
   • Duration: 6 weeks

3. Erythromycin
   (alternative to azithromycin)

   • Dose:
     • Adults: 500 mg orally twice daily
     • Children: 12.5 mg/kg orally four times daily
   • Duration: 14 days

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TI (Trachomatous Inflammation – Intense): Thickened, inflamed upper tarsal conjunctiva with pronounced redness.
TS (Trachomatous Scarring): Visible scarring of the tarsal conjunctiva.
TT (Trachomatous Trichiasis): Inturned eyelashes rubbing against the eyeball.
CO (Corneal Opacity): Opacity leading to significant visual impairment or blindness.
Mnemonic is FISTO.”
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Contraindications of Tooth Extraction

Introduction

Tooth extraction is a medical procedure that may not be suitable for all patients, especially those with certain health conditions. Below is a categorized list of general, local, absolute, and relative contraindications.

1. General Contraindications

These are conditions where tooth extraction should be avoided due to overall health concerns:

• Cardiac Diseases:

  • Valvular, Rheumatic, or Ischemic heart disease
  • Congestive heart failure
  • Hypertension
  • Patients on anticoagulation therapy

• Blood Diseases:

  • Severe anemia
  • Leukemia
  • Hemophilia
  • Agranulocytosis

• Addison’s Disease

• Patients on Corticosteroids:

  • Requires dose adjustment

• Liver Diseases:

  • Jaundice and liver disease
  • Vitamin K deficiency
  • Blood clotting factor deficiencies (Prothrombin, Fibrinogen)

• Diabetes Mellitus:

  • Poor wound healing due to decayed healing processes

• Thyrotoxicosis

• Pregnancy:

  • Especially during the first and third trimesters
  • Risks of abortion, premature delivery
  • Gravid uterus causing discomfort
  • Reduced stamina for opening the mouth

• Very Old Age:

  • Decreased physiological response
  • Non-healing tissues and increased risk of infection

• Epileptic Patients

• Presence of Fever:

  • Infections can complicate healing

• Debilitating Diseases:

  • Tuberculosis
  • Car pulmonale
  • Asthma
  • Nephritis

• Psychosis/Neurosis:

  • Mental health conditions affecting cooperation

• Allergy to Local Anesthetics (LA)

• Incorporative Patients:

  • Conditions where patient cooperation is compromised

• During Menstruation:

  • Hormonal changes may affect healing and tolerance

2. Local Contraindications

These are conditions that affect the immediate area of the tooth that may cause complications:

• Acute Infections:

  • Presence of infection at the extraction site

• Malignancy:

  • Growth may spread rapidly after the procedure

• Irradiated Jaw:

  • Risk of acute osteoradionecrosis due to lack of blood supply (endarteritis obliterans)

3. Absolute Contraindications

Certain conditions make tooth extraction entirely inappropriate:

• Hemangioma:

  • Increased risk of bleeding

• Arteriovenous Malformation (AV Malformation):

  • Bleeding that cannot be controlled

• In the case of such conditions, if extraction is necessary:

  • Place the tooth back in the socket and apply pressure to control bleeding

4. Relative Contraindications

These are conditions where tooth extraction may be performed with caution or special consideration:

• Diabetes Mellitus:

  • May require special management due to healing concerns

• Valvular Heart Disease:

  • And other similar conditions where dental management requires careful planning and monitoring

Casoni’s Test : Notes for Doctors

E granulosus lifecycle Souce and Copyright: CDC

 Casoni’s test is done to diagnose …

    a. Fascioliasis

    c. Hookworm

    b. Hydatid cyst

    d. Schistoomiasis

Solution

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Click to see answer

Ans: ‘b’
Casoni’s test (intradermal skin test) is an immediate hypersensitivity skin
test used in the diagnosis of hydatid cyst.

Echinococcus cyst cross section

Hydatid cyst

• Pathogenesis infection is acquired by grass/vegetables contaminated with
  dog feces containing larval cyst of E. granulosus.
• Man is dead end host & accidental host
• Dog is definitive host
• Cyst may occur in liver (m/c site in adults); lung (m/c site in
  children)

USG Finding in Hydatid Cyst

• USG is diagnostic (multiloculated cyst)

PAIR procedure for Hydatid cyst: 

Percutaneous puncture (P) of cyst under USG guidance, aspiration (A) of its
content, injection (I) of scolicidal agent & reaspiration (R). (for
small size < 5-6 cm).

Scolicidal agents for Hydatid Cyst

hypertonic 2% saline, sodium hypochloride, cetrimide, chlorhexidine

Common postoperative complications

Chronic Dental Conditions in the Elderly

Conditions that develop over a long period, particularly in older individuals, include attrition, abrasion, and erosion.

Attrition

Attrition refers to the wearing away of tooth substance due to mastication.

Causes:

• Coarse, gritty diet
• Nervous habits (e.g., grinding teeth during anxiety)
• Bruxism (grinding teeth at night)
• Chewing on pipes

Sites Affected:

• Anterior teeth: Incisal edges
• Posterior teeth: Occlusal surfaces

Clinical Features:

• Affected surfaces appear smooth and polished.
• In advanced cases, incisal edges and cusps wear away, appearing peg-like, while the occlusal surface becomes flat or even hollowed.
• Despite severe attrition, pulp exposure is rare due to compensatory dentine formation.
• Attrition is incompatible with caries and periodontal disease since these conditions lead to tooth destruction and mobility, preventing attrition from occurring.
• Attrition may have a protective role against caries by eliminating stagnation areas on occlusal surfaces.

Abrasion

Abrasion is the pathological wearing away of teeth by foreign substances.

Causes:

• Chewing tobacco
• Vigorous tooth brushing, especially with abrasive toothpaste
• Professions involving repetitive biting habits (e.g., cutting thread)
• Hard tooth brushing with a horizontal sweeping action (most common cause)

Sites Affected:

• Cervical region of teeth (near the cementoenamel junction)—most susceptible to abrasion
• Corner teeth—most severely affected

Clinical Features:

• Significant gingival recession is observed, but no gingivitis occurs due to effective plaque removal.
• Progressive exposure of cementum and dentine, leading to grooved defects.

Erosion

Erosion refers to the progressive dissolution of tooth structure, typically caused by acids, though some cases have unknown etiologies.

Causes:

• Occupational exposure (e.g., battery or acid factory workers exposed to acid fumes)
• Dietary factors:
  • Habitual sucking of citrus fruits for prolonged durations
  • Excessive consumption of carbonated soft drinks (high in phosphoric acid), leading to developmental caries
• Gastroesophageal conditions:
  • Chronic regurgitation of acidic gastric juice, as seen in acid peptic disease (APD), gastroesophageal reflux disease (GERD), and early pregnancy, predominantly affecting the palatal surface
• Erosion of unknown origin: Manifests as shallow, highly polished lesions on the labial surface

Treatment:

• Identification and elimination of the cause (occupational, dietary, medical factors)
• Application of protective coatings
• Use of fluoridated toothpaste
• Iontophoresis with sodium fluoride (NaF) for enamel reinforcement

GCS Calculator

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let eyeResponse = parseInt(document.getElementById(“eyeResponse”).value);
let verbalResponse = parseInt(document.getElementById(“verbalResponse”).value);
let motorResponse = parseInt(document.getElementById(“motorResponse”).value);

let totalGCS = eyeResponse + verbalResponse + motorResponse;
document.getElementById(“gcsScore”).innerText = totalGCS;

let severity = document.getElementById(“severity”);
if (totalGCS >= 13) {
severity.innerText = “🟢 Mild Brain Injury”;
} else if (totalGCS >= 9) {
severity.innerText = “🟡 Moderate Brain Injury”;
} else {
severity.innerText = “🔴 Severe Brain Injury”;
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